---
name: "Mutational Advantage"
mana_cost: "{1}{G}{U}"
cmc: 3
type_line: "Instant"
colors: ["G", "U"]
color_identity: ["G", "U"]
keywords: ["Proliferate"]
set: "SLD"
set_name: "Secret Lair Drop"
collector_number: "2454"
rarity: "rare"
artist: "Nicholas Gregory"
oracle_id: "2daa5b89-e772-4a2b-ad52-bbbf148c7b2f"
canonical_url: "https://avascry.com/printing/mutational-advantage-sld"
legalities:
  commander: "legal"
  standard: "not_legal"
  modern: "not_legal"
  pioneer: "not_legal"
  legacy: "legal"
  vintage: "legal"
  pauper: "not_legal"
  penny: "not_legal"
---

# Mutational Advantage
- **Mana Cost:** `{1}{G}{U}` (CMC: 3)
- **Type:** Instant
- **Keywords:** Proliferate

## Oracle Text
Permanents you control with counters on them gain hexproof and indestructible until end of turn. Prevent all damage that would be dealt to those permanents this turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

> *Not just surviving, but thriving!*

## Top 4096-Dim Neural Synergies
1. [Shields Up!](/printing/shields-up-trk.md) — Instant
2. [Tamiyo's Safekeeping](/printing/tamiyos-safekeeping-sld.md) — Instant
3. [Heroic Intervention](/printing/heroic-intervention-sld.md) — Instant
4. [Gaea's Gift](/printing/gaeas-gift-bro.md) — Instant
5. [Tyvar's Stand](/printing/tyvars-stand-soc.md) — Instant
6. [Repulsive Mutation](/printing/repulsive-mutation-mkm.md) — Instant

## Printing Details
- **Set:** Secret Lair Drop (SLD) #2454
- **Rarity:** Rare
- **Artist:** Nicholas Gregory
- **Total Printings:** 13 across all historical editions

## Format Legalities
Commander: `legal` | Standard: `not_legal` | Modern: `not_legal` | Pioneer: `not_legal` | Legacy: `legal` | Vintage: `legal` | Pauper: `not_legal` | Penny: `not_legal`